ADALTA corsi in italiano e acquisti software scientifico Intel software, Wolfram Mathematica, Origin, Statgraphics, EViews
Contatti | info@adalta.it Intel software, Wolfram Mathematica, Origin, Statgraphics, EViews
Intel software, Wolfram Mathematica, Origin, Statgraphics, EViews
Intel software, Wolfram Mathematica, Origin, Statgraphics, EViews
Info e Commerciali Intel software, Wolfram Mathematica, Origin, Statgraphics, EViews
Prism 8.3
Lingua: Ing S.O.: Win, Mac
Produttore: GraphPad
  ADALTA è Importatore Ufficiale e Rivenditore Autorizzato per l'Italia per i prodotti GraphPad

Analyze, graph and present your scientific work.

Prism è un ottimo software per la biostatistica di base e la grafica scientifica.
Grazie alla semplicità di approccio, alla potenza di analisi e di grafica negli esperimenti ripetitivi, all'applicazione del test statistico più appropriato, alla capacità di interpretazione dei risultati, Prism è il software ideale per l'applicazione nelle scienze della vita.

Quello che rende Prism unico non è tanto quello che fa, ma come lo fa.
Creato per i ricercatori di laboratorio e clinici, Prism guida l'utilizzatore privo di conoscenze statistiche attraverso il processo di analisi, supportandolo con tutto l'aiuto che necessita; è possibile così concentrarsi sui dati e non sul funzionamento del software.

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Why Choose Prism?

Save Time Performing Statistical Analyses

A versatile statistics tool purpose-built for scientists—not statisticians. Get a head start by entering data into tables that are structured for scientific research and guide you to statistical analyses that streamline your research workflow. No coding required.

Learn more

Make More Accurate, More Informed Analysis Choices

Gain insights and guidance at every step so you make the right analysis choices, understand the underlying assumptions, and accurately interpret your data along the way.

Learn more

Tell a Story With Your Data

Prism makes it easy to collaborate with colleagues, receive feedback from peers, and share your research with the world. Go from data to elegant, publication-quality graphs—with ease. Prism offers countless ways to customize your graphs, from color schemes to how you organize data. Export into almost any format, send to PowerPoint, or email directly from the application.

Learn more

 


 

Introducing Prism 8!

The most intuitive and sophisticated version of Prism yet.

Learn More

Resources

Master the key principles of statistics with GraphPad's hugely popular educational guides and resources.

Avoid Common Statistical Mistakes The Curve Fitting Guide QuickCalcs

Avoid Common Statistical Mistakes

Statistics help you understand patterns in the world. But analyzing data incorrectly can result in misleading or false conclusions when interpreting those patterns. This guide will help you avoid common mistakes that many textbooks barely mention.


The Curve Fitting Guide

Many scientists fit curves more often than they use any other statistical technique, yet many don’t really understand the principles. This guide provides a concise introduction to fitting curves, especially nonlinear regression.


QuickCalcs

Join the thousands of scientists that use one of our 25+ online calculators to run quick statical tests every day.

 

Features

The preferred analysis and graphing solution purpose-built for scientific research. Join the world's leading scientists and discover how you can use Prism to save time, make more appropriate analysis choices, and elegantly graph and present your scientific research.

Comprehensive Analysis and Powerful Statistics, Simplified

Organize Your Data Effectively

Unlike spreadsheets or other scientific graphing programs, Prism has eight different types of data tables specifically formatted for the analyses you want to run. This makes it easier to enter data correctly, choose suitable analyses, and create stunning graphs.

Perform The Right Analysis

Avoid statistical jargon. In clear language, Prism presents an extensive library of analyses from common to highly specific—nonlinear regression, t tests, nonparametric comparisons, one-, two- and three-way ANOVA, analysis of contingency tables, survival analysis, and much more. Each analysis has a checklist to help you understand the required statistical assumptions and confirm you have selected an appropriate test.

Get Actionable Help As You Go

Reduce the complexity of statistics. Prism’s online help goes beyond your expectations. At almost every step, access thousands of pages from the online Prism Guides. Browse the Graph Portfolio and learn how to make a wide range of graph types. Tutorial data sets also help you understand why you should perform certain analyses and how to interpret your results.


Work Smarter, Not Harder

One-Click Regression Analysis

No other program simplifies curve fitting like Prism. Select an equation and Prism does the rest—fits the curve, displays a table of results and function parameters, draws the curve on the graph, and interpolates unknown values.

Focus on Your Research, Not Your Software

No coding required. Graphs and results are automatically updated in real time. Any changes to the data and analyses—adding missed data, omitting erroneous data, correcting typos, or changing analysis choices—are reflected in results, graphs, and layouts instantaneously.

Automate Your Work Without Programming

Reduce tedious steps to analyze and graph a set of experiments. It is easy to replicate your work by creating a template, duplicating a family, or cloning a graph—saving you hours of set up time. Apply a consistent look to a set of graphs with one click using Prism Magic.


The Fastest Way to Elegantly Graph and Share Your Work

Countless Ways to Customize Your Graphs

Focus on the story in your data, not manipulating your software. Prism makes it easy to create the graphs you want. Choose the type of graph, and customize any part-how the data is arranged, the style of your data points, labels, fonts, colors, and much more. The customization options are endless.

Export Publication-Quality Graphs With One Click

Reduce time to publish. Prism allows you to customize your exports (file type, resolution, transparency, dimensions, color space RGB/CMYK) to meet the requirements of journals. Set your defaults to save time.

Enhance Collaboration

Share more than your graphs. Prism’s comprehensive record of your data enables effective collaboration with other scientists. All parts of your Prism project (raw data, analyses, results, graphs, and layouts) are contained in a single file that you can share with one click. Now others can easily follow your work at every step, enhancing the clarity of your findings and streamlining your collaborative efforts.


 

What's New

 

Prism 8.3.0 Release Notes

Introducing Logistic Regression

You've been asking for it, and we've delivered: Simple Logistic Regression and Multiple Logistic Regression are now available in Prism 8.3.0!

A quick overview

One of the most top-requested features has continuously been the ability to perform logistic regression with Prism. In many experiments, your measurement of interest can only take on one of two possible outcomes: yes or no, 1 or 0, "event occurred" or "event didn't occur". In these situations, the right analysis for the job is often logistic regression, and with the release of Prism 8.3.0, we're very excited to announce that this analysis is now available to you. In fact, Prism 8.3.0 actually introduces two separate - but very similar - analyses:

Simple Logistic Regression

Multiple Logistic Regression

Stay connected

Your feedback and suggestions made logistic regression in Prism a reality. Do you have other ideas for new features? Suggestions for improvements to existing features? Email us at suggestions@graphpad.com to let us know!

 

Complete Release Notes for Prism 8.3.0

New Features

  • Implemented Simple logistic regression from XY data tables
  • Implemented Multiple logistic regression from Multiple variables data tables

Feature Improvements

  • Added an alert regarding data mismatch for 'One-way ANOVA (and nonparametric or mixed)' analysis if data sets were excluded resulting in fewer than three data sets in the analysis
  • Updated the name of the 'Linear regression' analysis to 'Simple linear regression'
  • Added analytical representations of polynomial functions (5th, 6th, and 10th order)
  • Improved auto-recovery of Prism files under specific situations

Performance (Speed) Improvements

  • Improved performance of nonlinear regression that uses Gaddum-Schild equations
  • (Windows) Improved performance of copying and pasting data sets with a huge number of rows
  • (Windows) Improved performance of importing TXT data
  • (Windows) Improved performance of selecting thumbnails in the combined gallery view of Data+results sheets
  • (Mac) Improved performance when first switching to 'Open a File' tab on the Welcome dialog
  • (Mac) Improved Navigator performance for large projects

Analysis Bug Fixes

  • Fixed the issue in which the one-sample t-test produced empty results for replicated data if each subcolumn was analyzed separately
  • Fixed the issue in which LogEC50 and HillSlope results were replaced with "???" and the results for EC50 were empty when using the "Identify "unstable" parameters" option
  • Fixed the issue in which LOWESS/Smoothing splines would generate incorrect residuals when input XY table contained replicates
  • Fixed the Y title for the residual plot generated from Fit spline/LOWESS analysis
  • Improved the accuracy of interpolation on the bounds of the data range using Akima splines
  • Fixed the issue in which Prism would crash when performing "Transform" analysis with Rank Y transform and interchange XY, while one column contained a title but no data
  • Fixed the issue in which Normalize each sub column separately could not be selected in the Normalize dialog if the first data set was deleted from the source data table
  • Added a link to the Curve Fitting Guide from the descriptions of analyses of "Dose-response - Special, X is concentration" family
  • (Windows) Fixed the issue in which the "Subcolumns" section of the "Parameters: Normalize" dialog was unexpectedly greyed out if the first data set of the source data table was empty
  • (Windows) Fixed issue in which Prism would crash when performing 'Multiple linear regression' after adding more than 256 components to the model
  • (Windows) Fixed the issue in which "β0" was reported in the "Hook Constant" dialog if "Multiple Linear Regression" analysis was performed without an intercept
  • (Windows, 32-bit only) Fixed the issue in which Prism would crash while changing parameters for Two-way ANOVA when the result sheet was orphaned
  • (Mac) Fixed the issue in which the 'Geo. mean of ratios CI plot' results sheet of a t test appeared as "Mean, Upper Limit/Lower Limit" instead of "Geometric Mean/Upper Limit/Lower Limit"
  • (Mac) Fixed the issue in which 'narrative results' appeared corrupted after all source data sets except the first were deleted, followed by using the "Undo" operation
  • (Mac) Fixed the issue in which the "Number of segments" value was unexpectedly reset from a hooked value to the default in the "Fit Spline/LOWESS" dialog
  • (Mac) Updated links for the "Help" button in the "Parameters: Fit Spline/LOWESS" dialog and corresponding "Interpret" toolbar button
  • (Mac) Fixed the issue in which the "Mann-Whitney test" and "Kolmogorov-Smirnov test" radio buttons were incorrectly displayed after toggling between options in the t test dialog
  • (Mac) Renamed the tab in the "Parameters: Simulate XY data" dialog to "Parameter values & column titles" instead of "Parameter values"

Graphing Bug Fixes

  • Fixed the issue in which incorrect labels were displayed on the X axis of a Nested graph if data had been excluded or deleted from the data table
  • Fixed the issue in which long legends on a graph became disrupted in Mac Prism projects opened on Windows
  • Fixed the issue in which graph axes and labels would appear shifted from their positions after reopening the project
  • Fixed the issue in which graph axes and labels would shift from their positions when page orientation was changed
  • (Windows) Fixed the issue in which error bars on a column bar graph unexpectedly appeared thinner near the range limit of the axis
  • (Windows) Removed an unexpected thin gap between data sets on a Grouped graph when the settings for the "gap between adjacent data" was set to 0%
  • (Windows) Fixed the issue in which the left side of the graph appeared cut off on a layout sheet after deleting the Y axis title and changing the row label's font style
  • (Windows) Fixed the issue in which axes grid lines partially disappeared for one segment if the right Y axis and X axis were split into three segments
  • (Mac) Made it possible to change the color of spike bars using the Format Points contextual menu from a data table
  • (Mac) Fixed the issue in which the tooltip for heat map legends displayed truncated values
  • (Mac) Fixed the issue in which data point symbols on a graph unexpectedly appeared in a color different from the curve after adding transformed data to the graph and applying a color scheme
  • (Mac) Fixed the issue in which custom symbols which were taken from the "Character Palette" dialog lost their formatting after entering any text in the row title of the source data table
  • (Mac) Fixed the issue in which data sets that were added from a different data table to "Low-High", "Box & Whiskers", or "Violin" graphs from the Nested family incorrectly appeared as bars
  • (Mac) Fixed the issue in which the format of axes legends on a heat map were not applied after changing it from the "Powers of ten" option to "Decimal"
  • (Mac) Fixed the issue in which the default format for the right Y axis was incorrect if the "Ln (Natural Log)" scale was applied to the left Y axis
  • (Mac) Fixed the issue in which a heat map that was created from Correlation Matrix analysis appeared almost entirely black when the source data table contained a large number of data sets
  • (Mac) Fixed the issue in which vertical bar graphs with a custom baseline appeared distorted after changing the graph type to horizontal
  • (Mac) Fixed the issue in which annotation labels on a graph were cut if there was a gap in the axis
  • (Mac) Fixed the issue in which some error bars retained a gap - if the graph they were plotted on previously used a segmented axis - after the "Discontinuous axis" checkbox was unchecked in the Format Graph dialog

Other Bug Fixes

  • Fixed the issue in which Prism would crash when attempting to write over 257 symbols to Info Notes using a Prism script
  • Removed "ExportPCX" script command from the "Script Syntax" section of "GraphPad Prism Script" dialog
  • Fixed the link to the Curve Fitting Guide from the description of "Absolute IC50, X is log..." in the "Parameters: Nonlinear regression" dialog
  • Fixed the URL to the beta test page in the alert about beta expiration
  • Removed QQ plot as an option for Poisson regression in the "Parameters: Multiple Linear Regression" dialog
  • Improved floating note text: "This analysis was performed by a newer version of Prism, so it cannot be recalculated and it will not update when linked data are changed. Saving this file will result in parameters being lost if this file is re-opened in its original (newer) version."
  • Fixed the issue in which silent activation was not performed when a non-expired license existed
  • (Windows) Fixed the issue in which a range of highlighted cells was not updated accordingly after inserting a row or column
  • (Windows, 32-bit only) Fixed the issue in which Prism would crash upon opening very large projects, and added an alert about the inability of the 32-bit edition to open projects containing too many data points
  • (Windows) Fixed the issue in which Prism would hang after trying to check the "Three-way interactions" checkbox in the "Parameters: Multiple Linear Regression" dialog if the source data contained a huge amount of data
  • (Windows) Fixed the issue in which Prism would hang when switching to the "Compare" tab of the "Parameters: Multiple Linear Regression" dialog if the source data contained a huge number of columns
  • (Windows) Fixed the issue in which Prism would crash while performing Multiple Linear Regression with more than 100 independent variables
  • (Windows) Fixed the issue in which Prism would crash after breaking the link to an XLS file from the "Links" dialog if the data table contained data linked to a results sheet
  • (Windows) Fixed the issue in which Prism would crash after trying to delete all graphs, except for one from gallery mode
  • (Windows) Fixed the issue in which values could not be entered into the default cell of a new data table created from the "Data+Results" folder in the Navigator
  • (Windows) Fixed the issue in which thumbnails of results sheets became duplicated after deleting the source data table linked to at least three chained analyses in combined "Data+Results" view in the Navigator
  • (Windows) Fixed the issue in which Prism returned to gallery mode instead of sheet view when you double click a non-selected sheet from the gallery
  • (Windows) Fixed the issue in which the "Disk or memory error occurred" alert unexpectedly appeared in an attempt to paste transpose the data into the column title cell
  • (Windows) Fixed the issue in which the "Disk or memory error occurred" alert unexpectedly appeared when double-clicking in the graphing area of a "Parts of Whole" graph after its data had been deleted
  • (Windows) Fixed the issue in which the name of a graph sheet was unexpectedly changed after editing a linked column title from a data table with brackets [ ] in its name
  • (Windows) Fixed the issue in which cells copied from MS Excel and pasted into Prism as column titles did not affect the linked graph sheet name
  • (Windows) Fixed the issue in which Prism's log file generated by executing Prism's script appeared empty
  • (Windows) Fixed the issue in which Prism would crash while attempting to add a column title from the "Format Data Table" dialog
  • (Windows) Fixed the issue in which Prism would crash after switching to a Heat map which was created from the Correlation Matrix analysis if the source data contained a large number of data sets
  • (Windows) Fixed the issue in which Prism would crash when pressing the CTRL+L shortcut while no project was open
  • (Windows) Fixed the issue in which the names of all results sheets in the Data+results folder unexpectedly became bolded on re-ordering by dragging them in the Navigator
  • (Windows) Fixed the issue in which artifacts would appear on XY data tables with empty error cells during vertical scrolling
  • (Windows) Fixed the issue in which special characters were lost from linked info tables after performing the "Duplicate Family" operation twice
  • (Windows) Fixed the issue in which the "Run simulation again" toolbar button was absent for the "Simulate contingency table" results sheet
  • (Windows) Fixed the issue in which a graph thumbnail was not updated in the gallery after making any changes in the "Format Graph" dialog invoked from the toolbar
  • (Windows) Fixed the issue in which an info hint on the bottom toolbar did not change position and was truncated while resizing the Navigator
  • (Windows) Fixed the issue in which a results sheet was duplicated in "Go To Linked Sheet" contextual menu invoked from the Navigator
  • (Windows) Fixed the issue in which characters were ignored on pasting multi-word titles to column or subcolumn titles in the "Format Data Table" dialog
  • (Windows) Fixed the issue in which it was impossible to paste a single row of column or subcolumn titles in the Column (or Subcolumn) Titles tab of the "Format Data Table" dialog
  • (Windows) Fixed the "Format Graph" dialog look so that the edit field of the Baseline in the dialog was not corrupted when hovering the mouse over it
  • (Windows) Fixed the issue in which the "Line" formatting commands in the "Format points" and toolbar button dropdowns were mistakenly enabled for the "Scatter plot with bar" graph type
  • (Windows) Fixed the issue in which the graph preview was incorrect for vertical bar graphs with a custom baseline that had their graph type changed to horizontal
  • (Windows) Fixed the issue in which selection checkboxes on thumbnails in gallery mode were not scaled properly on high DPI displays
  • (Windows) Fixed the issue in which the "Hook" icon woudl disappear in the "Hook Constant" dialog on high DPI displays
  • (Windows) Fixed the issue in which elements of the Navigator would become corrupted and would overlap in the combined "Data+Results" folder view on high DPI displays
  • (Windows) Fixed the alignment of radio buttons in the "Measurement units" section of the Preferences dialog
  • (Windows) Fixed the issue in which unexpected symbols were shown in data set names in the "Select Data Sets" dialog
  • (Windows) Disabled the "Equalize scaling factor" toolbar button and menu item when there was a single graph on a layout
  • (Mac) Fixed the issue in which Prism would crash after switching to the graph sheet if the source data table was previously deleted and the undo operation was performed
  • (Mac) Fixed the issue in which Prism would crash while applying shortcuts for switching tabs (CMD+1/2/3...) in the results gallery after switching from sheet view for analysis with tabs
  • (Mac) Fixed the issue in which the wrong graph sheet is displayed after clicking the "Go To" button in the "Place Graph on Layout" dialog
  • (Mac) Fixed the issue in which an endless calculation process was shown after opening a file saved on a graph due to Prism mistakenly trying to show the "Change Graph Type" dialog while an analysis plotted on the graph was being recalculated
  • (Mac) Fixed the issue in which Prism unexpectedly displayed a different sheet after changing the sheet order in the Navigator
  • (Mac) Fixed the issue in which Prism would crash when switching between Prism and other apps after using a Prism script from the GraphPad Prism Script dialog
  • (Mac) Fixed the issue in which Prism would crash while attempting to run a script that opens a file with a name containing 255 characters
  • (Mac) Fixed the issue in which Prism would crash when opening the Nonlinear regression dialog if identically named .PZF and .PZT files with custom equations were used in the Equations folder
  • (Mac) Fixed the issue in which Prism would freeze while saving a Prism project to LabArchives after logging in to a different LabArchives account
  • (Mac) Fixed the issue in which Prism would select an incorrect range of sheets in the Navigator using the SHIFT modifier key in the combined "Data+Results" view in gallery mode
  • (Mac) Fixed the issue in which selected thumbnails did not disappear in the gallery mode after deleting them from the "Search Results" folder
  • (Mac) Fixed the issue in which changes made using the "Format This Violin" contextual menu on a violin plot did not propagate into the "Format Graph" dialog
  • (Mac) Fixed the issue in which it was not possible to edit "K" values and the "Title" field in the "Parameters: Select and Transform" dialog
  • (Mac) Fixed the issue in which selection arrows were non-functional in the "Parameters: Simulate 2 x 2 contingency table" dialog
  • (Mac) Fixed the issue in which decimal places were not automatically determined in a target table after pasting data with a link from a green results sheet to a data table
  • (Mac) Fixed the issue in which the number of subcolumns in the "Format Data Table" dialog were lost after switching between table types
  • (Mac) Fixed the issue in which a data table unexpectedly appeared instead of a results sheet after clicking "OK" in analysis parameters dialogs after inserting a new data table with a graph
  • (Mac) Fixed the issue in which it was impossible to select the 95% CI for Median and Error appearance in the "Format Graph" dialog for XY graphs
  • (Mac) Fixed the issue in which part of linked sheets were not deleted from the Navigator after performing the "Delete Entire Family" operation from the "Family" folder
  • (Mac) Fixed the issue in which the "Family" folder in the Navigator did not re-appear after performing the "Undo" operation after an entire family had been deleted
  • (Mac) Fixed the issue with syncing options when the wrong pattern style for a bar was shown in the "Format Graph" dialog after the pattern was previously changed using the contextual menu on a graph
  • (Mac) Fixed the issue in which thumbnails with results sheets unexpectedly appeared in the Navigator after performing the "Delete entire Family" command in gallery mode
  • (Mac) Fixed the issue in which the name of the first subcolumn appeared in a data table instead of "Mean" after a Nested data table was changed to an XY or Grouped data table with error bars calculated elsewhere
  • (Mac) Fixed the alignment of an indication on the bottom status bar of the currently selected cell in "Interpolated Y values"/"Interpolated X values" results of the "Fit Spline/LOWESS" analysis
  • (Mac) Fixed the corrupted hint in the annotation section of the RM Design tab in "Parameters: Two-way ANOVA" dialog when "Correct for multiple comparisons by controlling the False Discovery Rate" test was selected
  • (Mac) Fixed the issue in which the "Saved example" tab appeared empty after clicking the "Back" button in the "Clone Example" dialog if any graph was cloned previously
  • (Mac) Fixed the issue in which the "Script Log" tab on the "GraphPad Prism Script" dialog became greyed out when a script error occurs
  • (Mac) Fixed the issue in which the "Above Bar & Error Bar" sub-tab did not appear highlighted in the "Annotations" tab of the "Format Graph" dialog
  • (Mac) Fixed the issue in which Prism would paste data incorrectly after selecting the "After rows, start a new column" checkbox in the "Import and Paste Special" dialog

 

Discover What's New in Prism 8!

Introducing an even more powerful Prism featuring enhanced data visualization and graph customization, more intuitive navigation, and more sophisticated statistical analyses.


Enhanced Data Visualization

Violin plots

Visualize distributions of large data sets more clearly than with box-whisker or simple bar graphs

Subcolumn graphs

Organize related subsets of nested data in a single graph

Smoothing spline

Major improvements in showing general data trends through Akima splines and smoothing splines with improved control over the number of knots, or inflection points

No more smiles

More intelligent adjustments of data point positions in scatter plots for better looking graphs

Read More


Improved Graphing and Customization Options

Draw lines and brackets with centered text

Easily annotate your data with asterisks or custom labels

Automatically label bar graphs

Annotate your bar graphs with values for the means, medians, or sample sizes to emphasize what's important in your work

Improved grouped graphs

Easily create graphs that show both individual points (scatter) along with bars for mean (or median) and error bars

Read More


More Intuitive Navigation

Find related sheets easily

New family panel shows the family of sheets related to the current sheet, and chains of analyses are automatically indented

Easily navigate between multiple results tables

Analyses with multiple results tables now grouped into a single sheet with tabs for each result table; choose which tabs to show or hide

Improved Search

Search by sheets with highlights or notes of specified color


Now Featuring Eight Kinds of Data Tables

New: Multiple variables data table

Each row represents a different subject and each column is a different variable, allowing you to perform Multiple linear regression (including Poisson regression), extract subsets of data into other table types, or select and transform subsets of the data

New: Nested data table

Analyze and visualize data that contains subsets within related groups; Perform nested t tests and nested one-way ANOVA using data within these tables


More Sophisticated Statistical Analyses

Perform repeated measures ANOVA - even with missing data

Now Prism will automatically fit a mixed effects model to complete this analysis

Powerful Improvements in regular ANOVA

View cell, row, column, and grand means (or least square means when data is missing); test for homogeneity of variance. For one-way ANOVA, choose a test that does not assume homogeneous variances.

Nested t test and nested one-way ANOVA

Utilize new types of data tables to perform nested t-tests and nested ANOVA as well as multiple linear regression (including Poisson regression)

Graph residuals from multiple types of analyses

Test residuals for normality in four different ways, and choose from four different ways to display these residuals


Discover the Breadth of Statistical Features Available in Prism 8

Statistical Comparisons

  • Paired or unpaired t tests. Reports P values and confidence intervals.
  • Automatically generate volcano plot (difference vs. P value) from multiple t test analysis.
  • Nonparametric Mann-Whitney test, including confidence interval of difference of medians.
  • Kolmogorov-Smirnov test to compare two groups.
  • Wilcoxon test with confidence interval of median.
  • Perform many t tests at once, using False Discovery Rate (or Bonferroni multiple comparisons) to choose which comparisons are discoveries to study further.
  • Ordinary or repeated measures ANOVA followed by the Tukey, Newman-Keuls, Dunnett, Bonferroni or Holm-Sidak multiple comparison tests, the post-test for trend, or Fisher's Least Significant tests.
  • One-way ANOVA without assuming populations with equal standard deviations using Brown-Forsythe and Welch ANOVA, followed by appropriate comparisons tests (Games-Howell, Tamhane T2, Dunnett T3)
  • Many multiple comparisons test are accompanied by confidence intervals and multiplicity adjusted P values.
  • Greenhouse-Geisser correction so repeated measures one-, two-, and three-way ANOVA do not have to assume sphericity. When this is chosen, multiple comparison tests also do not assume sphericity.
  • Kruskal-Wallis or Friedman nonparametric one-way ANOVA with Dunn's post test.
  • Fisher's exact test or the chi-square test. Calculate the relative risk and odds ratio with confidence intervals.
  • Two-way ANOVA, even with missing values with some post tests.
  • Two-way ANOVA, with repeated measures in one or both factors. Tukey, Newman-Keuls, Dunnett, Bonferroni, Holm-Sidak, or Fisher's LSD multiple comparisons testing main and simple effects.
  • Three-way ANOVA (limited to two levels in two of the factors, and any number of levels in the third).
  • Analysis of repeated measures data (one-, two-, and three-way) using a mixed effects model (similar to repeated measures ANOVA, but capable of handling missing data).
  • Kaplan-Meier survival analysis. Compare curves with the log-rank test (including test for trend).
  • Comparison of data from nested data tables using nested t test or nested one-way ANOVA (using mixed effects model).

Nonlinear Regression

  • Fit one of our 105 built-in equations, or enter your own. Now including family of growth equations: exponential growth, exponential plateau, Gompertz, logistic, and beta (growth and then decay).
  • Enter differential or implicit equations.
  • Enter different equations for different data sets.
  • Global nonlinear regression - share parameters between data sets.
  • Robust nonlinear regression.
  • Automatic outlier identification or elimination.
  • Compare models using extra sum-of-squares F test or AICc.
  • Compare parameters between data sets.
  • Apply constraints.
  • Differentially weight points by several methods and assess how well your weighting method worked.
  • Accept automatic initial estimated values or enter your own.
  • Automatically graph curve over specified range of X values.
  • Quantify precision of fits with SE or CI of parameters. Confidence intervals can be symmetrical (as is traditional) or asymmetrical (which is more accurate).
  • Quantify symmetry of imprecision with Hougaard's skewness.
  • Plot confidence or prediction bands.
  • Test normality of residuals.
  • Runs or replicates test of adequacy of model.
  • Report the covariance matrix or set of dependencies.
  • Easily interpolate points from the best fit curve.
  • Fit straight lines to two data sets and determine the intersection point and both slopes.

Column Statistics

  • Calculate descriptive statistics: min, max, quartiles, mean, SD, SEM, CI, CV, skewness, kurtosis.
  • Mean or geometric mean with confidence intervals.
  • Frequency distributions (bin to histogram), including cumulative histograms.
  • Normality testing by four methods (new: Anderson-Darling).
  • Lognormality test and likelihood of sampling from normal (Gaussian) vs. lognormal distribution.
  • Create QQ Plot as part of normality testing.
  • One sample t test or Wilcoxon test to compare the column mean (or median) with a theoretical value.
  • Identify outliers using Grubbs or ROUT method.
  • Analyze a stack of P values, using Bonferroni multiple comparisons or the FDR approach to identify "significant" findings or discoveries.

Linear Regression and Correlation

  • Calculate slope and intercept with confidence intervals
  • Force the regression line through a specified point.
  • Fit to replicate Y values or mean Y.
  • Test for departure from linearity with a runs test.
  • Calculate and graph residuals in four different ways (including QQ plot).
  • Compare slopes and intercepts of two or more regression lines.
  • Interpolate new points along the standard curve.
  • Pearson or Spearman (nonparametric) correlation.
  • Multiple linear regression (including Poisson regression) using the new multiple variables data table.

Clinical (Diagnostic) Lab Statistics

  • Bland-Altman plots.
  • Receiver operator characteristic (ROC) curves.
  • Deming regression (type ll linear regression).

Simulations

  • Simulate XY, Column or Contingency tables.
  • Repeat analyses of simulated data as a Monte-Carlo analysis.
  • Plot functions from equations you select or enter and parameter values you choose.

Other Calculations

  • Area under the curve, with confidence interval.
  • Transform data.
  • Normalize.
  • Identify outliers.
  • Normality tests.
  • Transpose tables.
  • Subtract baseline (and combine columns).
  • Compute each value as a fraction of its row, column or grand total.

 

 

System Requirements

Prism 8 for Windows

  • Runs under either the 32- or 64-bit versions of Windows Vista, 7, 8 or 10. The installer will detect your version of Windows and install the 32- or 64-bit version of Prism accordingly.
  • Requires a display resolution of at least 800 x 540 pixels. So the lowest standard display resolution for Prism is 800 x 600.
  • Requires about 100 MB (megabytes) of space on the hard drive.
  • Must connect to the internet to verify the license when it is first activated and also at at least once every 30 days (or every 20 launches, whichever comes sooner).

Prism 8 for Mac

  • Runs under macOS X 10.9 (Mavericks) or later. If you use macOS 10.8, Prism will launch and seems to run OK, but we haven’t tested Prism thoroughly under this version of macOS and can’t provide much support. If you use 10.8, we urge you to update MacOS.
  • Note: Prism on Mac OS Catalina (10.15): https://www.graphpad.com/support/faqid/2161/
  • Requires a display with a resolution of at least 1024 x 768 pixels.
  • Requires about 130 MB (megabytes) of space on the hard drive.
  • Must connect to the internet to verify the license when it is first activated and also at at least once every 30 days (or every 20 launches, whichever comes sooner).

 

 

Acquista: Prism

 
Prova Demo: Prism